Wednesday 21 October Chaos and fury as Boris Johnson forces curbs on Greater Manchester. Andy Burnham warns of real hardship after bitter standoff over support package. London the worst city in Europe for health costs from air pollution. Study measured financial impact of car emissions on deaths, health and lost working days in urban areas. Polluted air killing half a million babies a year across globe. State of Global Air report says indoor air quality causing two-thirds of the deaths and affecting health in the womb. Exclusive: National Highways name sparks anger in Wales, which looks after its own roads. Submarine killer Peter Madsen recaptured after taking hostage in Denmark jail escape. May's challenge to government 'unlikely to be her last'. UK police 'unable to cope' if no-deal Brexit cuts EU data sharing. No deal: how Greater Manchester's Covid talks broke down. Lockdown conflict between regional and national authorities in Spain. Tier 3 Manchester: what are the true Covid patient figures? Hospital patient numbers were key to whether region entered tier 3. We look at the data. Greater Manchester tier 3 confusion is 'win-win' locally for Burnham. While some residents welcome end to uncertainty many feel progress Tories were making in region is now lost. Failure to act on Covid 'circuit breaker' will cost billions — Labour. Rishi Sunak accused of ignoring struggling businesses in constituency. Coronavirus: , children in England off school in one week. My final offer: Honest Bob checks his pockets for Covid loose change. UK Covid death toll rises by in highest daily increase for months. The volunteers lining up for Covid challenge trials. Hunt on for future Covid mutations that cause treatments to lose potency. Nigeria protests: security forces open fire on protesters in Lagos. Crackdown as rallies against police brutality continue in defiance of government curfew. France: teacher's killer 'exchanged texts' with father of pupil. New Yorker suspends Jeffrey Toobin for allegedly masturbating on Zoom call. A decade in the building, Madrid's showpiece hotel has everything Global report: record Covid cases and new lockdowns across Europe. Trump asks Barr to investigate dubious claims against Joe and Hunter Biden. US supreme court denies Republican bid to limit Pennsylvania mail-in-voting. Cat and mouse on the high seas: on the trail of China's vast squid fleet. Berlin: vandalism of museum artefacts 'linked to conspiracy theorists'. Greece extends wall on Turkish border as refugee row deepens. Next accused of destroying documents in equal pay claim. US justice department sues Google over accusation of illegal monopoly. Lawsuit accuses tech company of abusing its position to dominate search and search advertising.

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